Extracting Blueberry Pigments with Compressed Fluid Technology
A recent paper introduced a compressed fluid-based separation process that combines carbon dioxide and ethanol to isolate portisins previously hemi-synthesized from blueberry surplus anthocyanins. The performance of the two-step separation process was compared favorably to centrifugal partitional chromatography (CPC) and conventional reversed-phase liquid chromatography (RPLC) findings that were reported in terms of portisins content in the extract, process throughput, process efficiency, and total solvent used.
PLS-DA With Univariate Filtration Refines Discovery of Untargeted Metabolomics Data Using LC–MS
May 23rd 2024As opposed to targeted metabolomics which looks only at a predetermined set of metabolites or their pathways, an untargeted approach was preferred by this research team because of its unbiased yet still comprehensive nature.
Analyzing Dried Blood Spots for Steroids with LC-MS/MS
Researchers investigated the use of electric field in dried blood spot (DBS) sample preparation for the detection of steroids in newborns using liquid chromatography-tandem mass spectrometry (LC-MS/MS) using both regular electroporation cuvettes and a custom vial setup.